Ontology highlight
ABSTRACT:
SUBMITTER: Li WL
PROVIDER: S-EPMC7844850 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
ACS central science 20201219 1
As biocatalysts, enzymes are characterized by their high catalytic efficiency and strong specificity but are relatively fragile by requiring narrow and specific reactive conditions for activity. Synthetic catalysts offer an opportunity for more chemical versatility operating over a wider range of conditions but currently do not reach the remarkable performance of natural enzymes. Here we consider some new design strategies based on the contributions of nonlocal electric fields and thermodynamic ...[more]