Ontology highlight
ABSTRACT:
SUBMITTER: Zhao L
PROVIDER: S-EPMC7848451 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Zhao Lili L Zhang Yao Y Liu Jiaoxia J Yin Wei W Jin Dan D Wang Dandan D Zhang Wei W
Oncology research 20180501 9
MicroRNAs (miRNAs) are short endogenous noncoding RNAs that frequently play vital roles in many cancer types. Herein we demonstrated that miR-185 was remarkably downregulated in NSCLC tissues compared with adjacent normal tissues. A lower level of miR-185 was associated with lymph node metastasis. Functional assays showed that upregulation of miR-185 inhibited the proliferation, colony formation, and invasion capacities of NSCLC cells in vitro. Furthermore, we found that miR-185 suppressed the e ...[more]