Ontology highlight
ABSTRACT:
SUBMITTER: Palanki R
PROVIDER: S-EPMC7855052 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Palanki Rohan R Peranteau William H WH Mitchell Michael J MJ
Advanced drug delivery reviews 20201109
Advances in prenatal imaging, molecular diagnostic tools, and genetic screening have unlocked the possibility to treat congenital diseases in utero prior to the onset of clinical symptoms. While fetal surgery and in utero stem cell transplantation can be harnessed to treat specific structural birth defects and congenital hematological disorders, respectively, in utero gene therapy allows for phenotype correction of a wide range of genetic disorders within the womb. However, key challenges to rea ...[more]