Burden of prematurity-associated recurrent wheezing: caregiver missed work in the D-Wheeze trial.
Ontology highlight
ABSTRACT: Objective
This study describes the burden of prematurity-associated wheezing in black infants with respect to caregiver missed work.Study design
We analyzed data from the D-Wheeze trial (ClinicalTrials.gov identifier NCT01601847). Black infants between 28-0/7 to 36-6/7 weeks' gestational age at birth receiving <28 days of supplemental oxygen were enrolled. The primary outcome was missed work to care for the infant in the first year.Results
147/277 (53.1%) infants had caregivers who reported time off. In an adjusted model, vitamin D supplementation (OR 0.52 [95% CI 0.30-0.89]; P?=?0.018), recurrent wheeze (OR 2.26 [95% CI, 1.15-4.44]; P?=?0.018), and other children in the household <5 years old (OR 0.45 [95% CI 0.26-0.78]; P?=?0.004) were significantly associated with caregiver missed work.Conclusions
Black premature infants had a significant burden of caregiver missed work, emphasizing the impact of prematurity-associated wheezing.
SUBMITTER: Ledingham L
PROVIDER: S-EPMC7855497 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Publications
Burden of prematurity-associated recurrent wheezing: caregiver missed work in the D-Wheeze trial.
Ledingham Lauren L Tatsuoka Curtis C Minich Nori N Ross Kristie R KR Kerns Leigh Ann LA Wagner Carol L CL Fuloria Mamta M Groh-Wargo Sharon S Zimmerman Teresa T Hibbs Anna Maria AM
Journal of perinatology : official journal of the California Perinatal Association 20200721 1
<h4>Objective</h4>This study describes the burden of prematurity-associated wheezing in black infants with respect to caregiver missed work.<h4>Study design</h4>We analyzed data from the D-Wheeze trial (ClinicalTrials.gov identifier NCT01601847). Black infants between 28-0/7 to 36-6/7 weeks' gestational age at birth receiving <28 days of supplemental oxygen were enrolled. The primary outcome was missed work to care for the infant in the first year.<h4>Results</h4>147/277 (53.1%) infants had care ...[more]
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