Ontology highlight
ABSTRACT:
SUBMITTER: Cerri S
PROVIDER: S-EPMC7856304 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Cerri Stefano S Puonti Oula O Meier Dominik S DS Wuerfel Jens J Mühlau Mark M Siebner Hartwig R HR Van Leemput Koen K
NeuroImage 20201022
Here we present a method for the simultaneous segmentation of white matter lesions and normal-appearing neuroanatomical structures from multi-contrast brain MRI scans of multiple sclerosis patients. The method integrates a novel model for white matter lesions into a previously validated generative model for whole-brain segmentation. By using separate models for the shape of anatomical structures and their appearance in MRI, the algorithm can adapt to data acquired with different scanners and ima ...[more]