Ontology highlight
ABSTRACT:
SUBMITTER: Goetz MJ
PROVIDER: S-EPMC7865378 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Goetz Maurizio J MJ Kremer Sarah S Behnke Judith J Staude Birte B Shahzad Tayyab T Holzfurtner Lena L Chao Cho-Ming CM Morty Rory E RE Bellusci Saverio S Ehrhardt Harald H
International journal of molecular sciences 20210124 3
Bronchopulmonary dysplasia (BPD) remains one of the most devastating consequences of preterm birth resulting in life-long restrictions in lung function. Distorted lung development is caused by its inflammatory response which is mainly provoked by mechanical ventilation, oxygen toxicity and bacterial infections. Dysfunction of resident lung mesenchymal stem cells (MSC) represents one key hallmark that drives BPD pathology. Despite all progress in the understanding of pathomechanisms, therapeutics ...[more]