Ontology highlight
ABSTRACT:
SUBMITTER: Kim DU
PROVIDER: S-EPMC7866969 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Kim Dong-Uk DU Kim Dong-Gu DG Choi Ji-Won JW Shin Joon Yeon JY Kweon Bitna B Zhou Ziqi Z Lee Ho-Sub HS Song Ho-Joon HJ Bae Gi-Sang GS Park Sung-Joo SJ
International journal of molecular sciences 20210131 3
Cisplatin is the most widely used chemotherapeutic agent. However, it often causes nephrotoxicity, which results in acute kidney injury (AKI). Therefore, we urgently need a drug that can reduce the nephrotoxicity induced by cisplatin. Loganin is a major iridoid glycoside isolated from Corni fructus that has been used as an anti-inflammatory agent in various pathological models. However, the renal protective activity of loganin remains unclear. In this study, to examine the protective effect of l ...[more]