Ontology highlight
ABSTRACT:
SUBMITTER: Fisher E
PROVIDER: S-EPMC7873992 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Fisher Eva E Padula Laura L Podack Kristin K O'Neill Katelyn K Seavey Matthew M MM Jayaraman Padmini P Jasuja Rahul R Strbo Natasa N
Frontiers in immunology 20210126
Given the aggressive spread of COVID-19-related deaths, there is an urgent public health need to support the development of vaccine candidates to rapidly improve the available control measures against SARS-CoV-2. To meet this need, we are leveraging our existing vaccine platform to target SARS-CoV-2. Here, we generated cellular heat shock chaperone protein, glycoprotein 96 (gp96), to deliver SARS-CoV-2 protein S (spike) to the immune system and to induce cell-mediated immune responses. We showed ...[more]