Ontology highlight
ABSTRACT:
SUBMITTER: Dearlove B
PROVIDER: S-EPMC7877758 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Dearlove Bethany B Tovanabutra Sodsai S Owen Christopher L CL Lewitus Eric E Li Yifan Y Sanders-Buell Eric E Bose Meera M O'Sullivan Anne-Marie AM Kijak Gustavo G Miller Shana S Poltavee Kultida K Lee Jenica J Bonar Lydia L Harbolick Elizabeth E Ahani Bahar B Pham Phuc P Kibuuka Hannah H Maganga Lucas L Nitayaphan Sorachai S Sawe Fred K FK Kim Jerome H JH Eller Leigh Anne LA Vasan Sandhya S Gramzinski Robert R Michael Nelson L NL Robb Merlin L ML Rolland Morgane M
PLoS computational biology 20210201 2
While large datasets of HIV-1 sequences are increasingly being generated, many studies rely on a single gene or fragment of the genome and few comparative studies across genes have been done. We performed genome-based and gene-specific Bayesian phylogenetic analyses to investigate how certain factors impact estimates of the infection dates in an acute HIV-1 infection cohort, RV217. In this cohort, HIV-1 diagnosis corresponded to the first RNA positive test and occurred a median of four days afte ...[more]