Ontology highlight
ABSTRACT:
SUBMITTER: Wang H
PROVIDER: S-EPMC7878461 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Wang Huan H Zhang Zui Z Guan Juan J Lu Weiyue W Zhan Changyou C
Asian journal of pharmaceutical sciences 20200727 1
Glucose transporter (GLUT)-mediated transcytosis has been validated as an efficient method to cross the blood-brain barrier and enhance brain transport of nanomedicines. However, the transcytosis process remains elusive. Glycopeptide-modified nanodisks (Gly-A7R-NDs), which demonstrated high capacity of brain targeting via GLUT-mediated transcytosis in our previous reports, were utilized to better understand the whole transcytosis process. Gly-A7R-NDs internalized brain capillary endothelial cell ...[more]