Ontology highlight
ABSTRACT:
SUBMITTER: Huang D
PROVIDER: S-EPMC7880331 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Huang Dongdong D Siaw-Debrah Felix F Wang Hua H Ye Sheng S Wang Kankai K Wu Ke K Zhang Ying Y Wang Hao H Yao Chaojie C Chen Jiayu J Yan Lin L Zhang Chun-Li CL Zhuge Qichuan Q Yang Jianjing J
Aging 20201219 2
Bone marrow mesenchymal stem cells (BMMSCs)-based therapy has emerged as a promising novel therapy for Traumatic Brain Injury (TBI). However, the therapeutic quantity of viable implanted BMMSCs necessary to initiate efficacy is still undetermined. Increased oxidative stress following TBI, which leads to the activation of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase signaling pathway, has been implicated in accounting for the diminished graft survival and therapeutic effect. To pro ...[more]