Ontology highlight
ABSTRACT:
SUBMITTER: Carmeille R
PROVIDER: S-EPMC7880465 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Carmeille Romain R Schiano Lomoriello Porfirio P Devarakonda Parvathi M PM Kellermeier Jacob A JA Heaslip Aoife T AT
PLoS pathogens 20210202 2
Toxoplasma gondii is an obligate intracellular parasite that relies on three distinct secretory organelles, the micronemes, rhoptries, and dense granules, for parasite survival and disease pathogenesis. Secretory proteins destined for these organelles are synthesized in the endoplasmic reticulum (ER) and sequentially trafficked through a highly polarized endomembrane network that consists of the Golgi and multiple post-Golgi compartments. Currently, little is known about how the parasite cytoske ...[more]