Ontology highlight
ABSTRACT:
SUBMITTER: Hade EM
PROVIDER: S-EPMC7885462 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Hade Erinn M EM Nattino Giovanni G Frey Heather A HA Lu Bo B
Statistical methods in medical research 20191001 3
In observational studies with a survival outcome, treatment initiation may be time dependent, which is likely to be affected by both time-invariant and time-varying covariates. In situations where the treatment is necessary for the study population, all or most subjects may be exposed to the treatment sooner or later. In this scenario, the causal effect of interest is the delay in treatment reception. A simple comparison of those receiving treatment early vs. those receiving treatment late might ...[more]