The effects of submaximal exercise and cold exposure on blood coagulation parameters in coronary artery disease patients.

ABSTRACT:

Background

Both exercise and cold exposure increase blood coagulation potential but their combined effects are not known. The purpose of the present study was to assess blood coagulation factors in response to submaximal exercise in the cold environment among patients with stable coronary artery disease (CAD).

Methods

Sixteen men (61.1 ± 7.1 years) with stable CAD participated in three 30-min experimental conditions (seated rest in - 15 °C and exercise in both + 22 °C and - 15 °C) in random order. The employed exercise consisted of brisk walking (66-69% of maximal heart rate). Factor VII (FVII), fibrinogen, D-dimer and von Willebrand factor (vWF) were analyzed from blood samples obtained before, immediately and one hour after each experiment.

Results

On average, FVII

SUBMITTER: Parkkila K 

PROVIDER: S-EPMC7885551 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature