Ontology highlight
ABSTRACT:
SUBMITTER: Williams MTJ
PROVIDER: S-EPMC7885690 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
ACS sustainable chemistry & engineering 20201123 48
A ball-milling enabled tertiary amine catalyzed aza-Morita-Baylis-Hillman reaction is reported. The reaction process does not require solvent, has significantly shorter reaction times than previous methods and is reported on a range of imines and acrylate Michael acceptors across than 26 examples. A 12-fold scaled-up example is also reported as well as experimental comparisons to solution-based experiments and neat-stirred reactions. ...[more]