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Dilatancy behaviour and permeability evolution of sandstone subjected to initial confining pressures and unloading rates.

ABSTRACT: Mechanical response, deformation behaviour and permeability evolution of surrounding rock under unloading conditions are of significant importance in rock engineering activities. In this research, triaxial experiments of sandstone subjected to different initial confining pressures and unloading rates under fixed axial stress were conducted. The results showed that sandstones experienced shear dilatancy before failure. However, the dilatancy factor did not decrease with increasing confining pressure, i.e. the dilatancy behaviour was not suppressed, which contradicted the phenomenon under increasing axial stress. The crack density also increased with increasing initial confining pressure. Furthermore, the normalized permeability was positively correlated with unloading rates. The sandstone permeability was closely related to the shear dilatancy behaviour. In the accelerated dilatancy stage, the relationship between normalized permeability and volumetric strain was linear at low unloading rates and nonlinear at high unloading rates. The linear/nonlinear relationship between them can directly affect the temporality of respective mutation, so as to guide the prevention of geological disasters at different excavations rates.

SUBMITTER: Zhao H

PROVIDER: S-EPMC7890488 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature

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Dilatancy behaviour and permeability evolution of sandstone subjected to initial confining pressures and unloading rates.

Zhao Honggang H Liu Chao C Huang Gun G

Royal Society open science 20210106 1

Mechanical response, deformation behaviour and permeability evolution of surrounding rock under unloading conditions are of significant importance in rock engineering activities. In this research, triaxial experiments of sandstone subjected to different initial confining pressures and unloading rates under fixed axial stress were conducted. The results showed that sandstones experienced shear dilatancy before failure. However, the dilatancy factor did not decrease with increasing confining press ...[more]

PMID: 33614098

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Project description:The long-term deformation and permeability evolution with time are key issues for geo-engineering applications such as radioactive waste disposal. Rock permeability concurrent with deformation is significantly influenced by cracking. This study investigated the creep-permeability evolution behavior of red sandstone specimens containing a single fissure under a confining pressure of 30 MPa. First, the effects of stress ratio (SR) and fissure dip angle on the creep behavior of rock were investigated. The more loading/unloading cyclic numbers, the larger the irrecoverable axial deformation. The instant elastic strains and visco-elastic strains linearly increased with SR for both the intact and fissured specimens, whereas the instant plastic strains showed different results. The visco-plastic strains nonlinearly increased. For fissured and intact specimens, the creep strains and the steady-state creep rates nonlinearly increased as SR increased. The instantaneous strains, instant elastic strains, and visco-elastic strains slightly varied when the fissure dip angle was less than 45° but notably decreased with increasing fissure dip angle beyond 45°. However, the fissure dip angle had no obvious effects on the plastic and creep strains. Damage (D) was defined using the ratio of non-elastic strains to the total strain. D increased approximately linearly with SR, but the fissure dip angle had no obvious influences. Subsequently, the long-term strength (LTS) of the red sandstone was determined using two different methods. The LTS first decreased when the fissure dip angle increased from 0 to 45° but increased with increasing dip angle. The triaxial and creep failure modes were mainly shear along anti-wing cracks for the fissured specimens but shear failure occurred for the intact specimen. Moreover, the permeability of the fissured red sandstone was governed by SR and deformation or time. During the multi-step loading/unloading creep process, the permeability first decreased and then had a sudden rise when tertiary creep occurred.

Project description:Collective cell migrations are essential in several physiological processes and are driven by both chemical and mechanical cues. The roles of substrate stiffness and confinement on collective migrations have been investigated in recent years, however few studies have addressed how geometric shapes influence collective cell migrations. Here, we address the hypothesis that the relative position of a cell within the confinement influences its motility. Monolayers of two types of epithelial cells--MCF7, a breast epithelial cancer cell line, and MDCK, a control epithelial cell line--were confined within circular, square, and cross-shaped stencils and their migration velocities were quantified upon release of the constraint using particle image velocimetry. The choice of stencil geometry allowed us to investigate individual cell motility within convex, straight and concave boundaries. Cells located in sharp, convex boundaries migrated at slower rates than those in concave or straight edges in both cell types. The overall cluster migration occurred in three phases: an initial linear increase with time, followed by a plateau region and a subsequent decrease in cluster speeds. An acto-myosin contractile ring, present in the MDCK but absent in MCF7 monolayer, was a prominent feature in the emergence of leader cells from the MDCK clusters which occurred every ~125 ?m from the vertex of the cross. Further, coordinated cell movements displayed vorticity patterns in MDCK which were absent in MCF7 clusters. We also used cytoskeletal inhibitors to show the importance of acto-myosin bounding cables in collective migrations through translation of local movements to create long range coordinated movements and the creation of leader cells within ensembles. To our knowledge, this is the first demonstration of how bounding shapes influence long-term migratory behaviours of epithelial cell monolayers. These results are important for tissue engineering and may also enhance our understanding of cell movements during developmental patterning and cancer metastasis.

Project description:BACKGROUND: Interlocus conflict predicts (a) evolution of traits, beneficial to males but detrimental to females and (b) evolution of aging and life-span under the influence of the cost of bearing these traits. However, there are very few empirical investigations shedding light on these predictions. Those that do address these issues, mostly reported response of male reproductive traits or the lack of it and do not address the life-history consequence of such evolution. Here, we test both the above mentioned predictions using experimental evolution on replicate populations of Drosophila melanogaster. We present responses observed after >45 generations of altered levels of interlocus conflict (generated by varying the operational sex ratio). RESULTS: Males from the male biased (high conflict, M-regime) regime evolved higher spontaneous locomotor activity and courtship frequency. Females exposed to these males were found to have higher mortality rate. Males from the female biased regime (low conflict, F-regime) did not evolve altered courtship frequency and activity. However, progeny production of females continuously exposed to F-males was significantly higher than the progeny production of females exposed to M-males indicating that the F-males are relatively benign towards their mates. We found that males from male biased regime lived shorter compared to males from the female biased regime. CONCLUSION: F-males (evolving under lower levels of sexual conflict) evolved decreased mate harming ability indicating the cost of maintenance of the suit of traits that cause mate-harm. The M-males (evolving under higher levels sexual conflict) caused higher female mortality indicating that they had evolved increased mate harming ability, possibly as a by product of increased reproduction related activity. There was a correlated evolution of life-history of the M and F-males. M-regime males lived shorter compared to the males from F-regime, possibly due to the cost of investing more in reproductive traits. In combination, these results suggest that male reproductive traits and life-history traits can evolve in response to the altered levels of interlocus sexual conflict.

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Dilatancy behaviour and permeability evolution of sandstone subjected to initial confining pressures and unloading rates.

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Dilatancy behaviour and permeability evolution of sandstone subjected to initial confining pressures and unloading rates.

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