Ontology highlight
ABSTRACT:
SUBMITTER: Long LJ
PROVIDER: S-EPMC7891302 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Long Lindsey J LJ Lee Po-Hsuen PH Small Eric M EM Hillyer Cory C Guo Yan Y Osley Mary Ann MA
DNA repair 20200430
Non-growing quiescent cells face special challenges when repairing lesions produced by exogenous DNA damaging agents. These challenges include the global repression of transcription and translation and a compacted chromatin structure. We investigated how quiescent yeast cells regulated the repair of DNA lesions produced by UV irradiation. We found that UV lesions were excised and repaired in quiescent cells before their re-entry into S phase, and that lesion repair was correlated with high level ...[more]