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Practical Considerations for Atomistic Structure Modeling with Cryo-EM Maps.

ABSTRACT: We describe common approaches to atomistic structure modeling with single particle analysis derived cryo-EM maps. Several strategies for atomistic model building and atomistic model fitting methods are discussed, including selection criteria and implementation procedures. In covering basic concepts and caveats, this short perspective aims to help facilitate active discussion between scientists at different levels with diverse backgrounds.

SUBMITTER: Kim DN

PROVIDER: S-EPMC7891309 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature

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Practical Considerations for Atomistic Structure Modeling with Cryo-EM Maps.

Kim Doo Nam DN Gront Dominik D Sanbonmatsu Karissa Y KY

Journal of chemical information and modeling 20200518 5

We describe common approaches to atomistic structure modeling with single particle analysis derived cryo-EM maps. Several strategies for atomistic model building and atomistic model fitting methods are discussed, including selection criteria and implementation procedures. In covering basic concepts and caveats, this short perspective aims to help facilitate active discussion between scientists at different levels with diverse backgrounds. ...[more]

PMID: 32422044

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