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Effect of normobaric hypoxic exercise on blood pressure in old individuals.


ABSTRACT:

Purpose

To test the hypothesis that the combination of endurance training and hypoxia leads to greater improvements in resting and exercise blood pressure in old sedentary individuals compared to endurance training only.

Methods

We randomly assigned 29 old overweight participants (age: 62?±?6 years, body mass index (BMI): 28.5?±?0.5 kg/m2, 52% men) to single blind 8-week bicycle exercise in hypoxia (fraction of inspired oxygen (FIO2)?=?0.15) or normoxia (FIO2?=?0.21). Brachial blood pressure was measured at rest, during maximal incremental exercise testing, and during a 30 min constant work rate test, at baseline and after the training period.

Results

Work rate, heart rate and perceived exertion during training were similar in both groups, with lower oxygen saturation for participants exercising under hypoxia (88.7?±?1.5 vs. 96.2?±?1.2%, t(27)?=?-?13.04, p?2?=?0.01).

Conclusion

In old individuals hypoxia in addition to exercise does not have superior effects on office or exercise blood pressure compared to training in normoxia.

Trial registration number

ClinicalTrials.gov No. NCT02196623 (registered 22 July 2014).

SUBMITTER: Hein M 

PROVIDER: S-EPMC7892684 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature

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Publications

Effect of normobaric hypoxic exercise on blood pressure in old individuals.

Hein Markus M   Chobanyan-Jürgens Kristine K   Tegtbur Uwe U   Engeli Stefan S   Jordan Jens J   Haufe Sven S  

European journal of applied physiology 20201223 3


<h4>Purpose</h4>To test the hypothesis that the combination of endurance training and hypoxia leads to greater improvements in resting and exercise blood pressure in old sedentary individuals compared to endurance training only.<h4>Methods</h4>We randomly assigned 29 old overweight participants (age: 62 ± 6 years, body mass index (BMI): 28.5 ± 0.5 kg/m<sup>2</sup>, 52% men) to single blind 8-week bicycle exercise in hypoxia (fraction of inspired oxygen (F<sub>I</sub>O<sub>2</sub>) = 0.15) or nor  ...[more]

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