Ontology highlight
ABSTRACT:
SUBMITTER: Fuhrer S
PROVIDER: S-EPMC7892832 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Scientific reports 20210218 1
A major proportion of allergic reactions to hazelnuts (Corylus avellana) are caused by immunologic cross-reactivity of IgE antibodies to pathogenesis-related class 10 (PR-10) proteins. Intriguingly, the four known isoforms of the hazelnut PR-10 allergen Cor a 1, denoted as Cor a 1.0401-Cor a 1.0404, share sequence identities exceeding 97% but possess different immunologic properties. In this work we describe the NMR solution structures of these proteins and provide an in-depth study of their bio ...[more]