Ontology highlight
ABSTRACT:
SUBMITTER: Benard A
PROVIDER: S-EPMC7893044 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Nature communications 20210218 1
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a worldwide health threat. In a prospective multicentric study, we identify IL-3 as an independent prognostic marker for the outcome during SARS-CoV-2 infections. Specifically, low plasma IL-3 levels is associated with increased severity, viral load, and mortality during SARS-CoV-2 infections. Patients with severe COVID-19 exhibit also reduced circulating plasmacytoid dendritic cells (pDCs) and low plasma IFNα and IFNλ levels when c ...[more]