Unknown

Dataset Information

0

Lewis Acid Promoted Dearomatization of Naphthols.

ABSTRACT: Two-step dearomative functionalization of naphthols promoted by Lewis acids and copper(I) catalysis was developed. Initially, Lewis acid complexation inverted the electronic properties of the ring and established an equilibrium with the dearomatized counterpart. Subsequent trapping of the dearomatized intermediate with organometallics as well as organophosphines was demonstrated and provided the corresponding dearomatized products.

SUBMITTER: Kulish K 

PROVIDER: S-EPMC7894535 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature

Json Xml
altmetric image

Publications

Lewis Acid Promoted Dearomatization of Naphthols.

Kulish Kirill K   Boldrini Cosimo C   Castiñeira Reis Marta M   Pérez Juana M JM   Harutyunyan Syuzanna R SR  

Chemistry (Weinheim an der Bergstrasse, Germany) 20201118 68

Two-step dearomative functionalization of naphthols promoted by Lewis acids and copper(I) catalysis was developed. Initially, Lewis acid complexation inverted the electronic properties of the ring and established an equilibrium with the dearomatized counterpart. Subsequent trapping of the dearomatized intermediate with organometallics as well as organophosphines was demonstrated and provided the corresponding dearomatized products. ...[more]

Similar Datasets

Unknown Chiral phosphoric acid catalyzed aminative dearomatization of α-naphthols/Michael addition sequence.
| S-EPMC6637135 | biostudies-literature
Unknown Organocatalytic asymmetric chlorinative dearomatization of naphthols.
| S-EPMC5707459 | biostudies-other
Unknown A Lewis acid-promoted Pinner reaction.
| S-EPMC3740506 | biostudies-literature
Unknown Catalytic asymmetric hydroxylative dearomatization of 2-naphthols: synthesis of lacinilene derivatives.
| S-EPMC5625263 | biostudies-literature
Unknown Construction of spirocarbocycles via gold-catalyzed intramolecular dearomatization of naphthols.
| S-EPMC6006865 | biostudies-other
Unknown Lewis Acid-Promoted Enantioselective Dearomative Spirocyclizations of Allenes.
| S-EPMC6173636 | biostudies-literature
Unknown Vinylazaarenes as dienophiles in Lewis acid-promoted Diels-Alder reactions.
| S-EPMC8672738 | biostudies-literature
Unknown Lewis acid-promoted Friedel-Crafts alkylation reactions with alpha-ketophosphate electrophiles.
| S-EPMC2852482 | biostudies-literature
Unknown Lewis acid-promoted [2 + 2] cycloadditions of alkenes with aryl ketenes.
| S-EPMC4814371 | biostudies-literature
Unknown Stereoselective Synthesis of Substituted Oxocene Cores by Lewis Acid Promoted Cyclization.
| S-EPMC5317094 | biostudies-literature