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Magnetic resonance thermometry using a GdIII-based contrast agent.


ABSTRACT: The complexes described here serve as contrast agents for magnetic resonance imaging thermometry. The complexes differentially enhance contrast between 275 and 325 K. The basis of the temperature response of the fluorinated contrast complex is the modulation of water exchange caused by trifluoromethyl groups that can be chemically controlled.

SUBMITTER: Subasinghe SAAS 

PROVIDER: S-EPMC7897303 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature

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Magnetic resonance thermometry using a Gd<sup>III</sup>-based contrast agent.

Subasinghe S A Amali S SAAS   Romero Jonathan J   Ward Cassandra L CL   Bailey Matthew D MD   Zehner Donna R DR   Mehta Prakrut J PJ   Carniato Fabio F   Botta Mauro M   Yustein Jason T JT   Pautler Robia G RG   Allen Matthew J MJ  

Chemical communications (Cambridge, England) 20210121 14


The complexes described here serve as contrast agents for magnetic resonance imaging thermometry. The complexes differentially enhance contrast between 275 and 325 K. The basis of the temperature response of the fluorinated contrast complex is the modulation of water exchange caused by trifluoromethyl groups that can be chemically controlled. ...[more]

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