Large-Amplitude Conformational Changes in Self-Assembled Multi-Stranded Aromatic Sheets.
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ABSTRACT:
SUBMITTER: Atcher J
PROVIDER: S-EPMC7898896 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Publications
Large-Amplitude Conformational Changes in Self-Assembled Multi-Stranded Aromatic Sheets.
Atcher Joan J Mateus Pedro P Kauffmann Brice B Rosu Frédéric F Maurizot Victor V Huc Ivan I
Angewandte Chemie (International ed. in English) 20201130 5
The orchestration of ever larger conformational changes is made possible by the development of increasingly complex foldamers. Aromatic sheets, a rare motif in synthetic foldamer structures, have been designed so as to form discrete stacks of intercalated aromatic strands through the self-assembly of two identical subunits. Ion-mobility ESI-MS confirms the formation of compact dimers. X-ray crystallography reveals the existence of two distinct conformational dimeric states that require large cha ...[more]
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