Interaction between cognitive reserve and age moderates effect of lesion load on stroke outcome.
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ABSTRACT:
SUBMITTER: Umarova RM
PROVIDER: S-EPMC7904829 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Publications
Interaction between cognitive reserve and age moderates effect of lesion load on stroke outcome.
Umarova Roza M RM Schumacher Lena V LV Schmidt Charlotte S M CSM Martin Markus M Egger Karl K Urbach Horst H Hennig Jürgen J Klöppel Stefan S Kaller Christoph P CP
Scientific reports 20210224 1
The concepts of brain reserve and cognitive reserve were recently suggested as valuable predictors of stroke outcome. To test this hypothesis, we used age, years of education and lesion size as clinically feasible coarse proxies of brain reserve, cognitive reserve, and the extent of stroke pathology correspondingly. Linear and logistic regression models were used to predict cognitive outcome (Montreal Cognitive Assessment) and stroke-induced impairment and disability (NIH Stroke Scale; modified ...[more]
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