Ontology highlight
ABSTRACT:
SUBMITTER: Zhao M
PROVIDER: S-EPMC7904900 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Zhao Miaomiao M Ying Lixiong L Wang Rusha R Yao Jiping J Zhu Liming L Zheng Min M Chen Zhi Z Yang Zhenggang Z
Frontiers in medicine 20210211
Autophagy is a highly conserved process by which superfluous or harmful components in eukaryotic cells are degraded by autophagosomes. This cytoprotective mechanism is strongly related to various human diseases, such as cancer, autoimmune diseases, and diabetes. DEAH-box helicase 15 (DHX15), a member of the DEAH box family, is mainly involved in RNA splicing and ribosome maturation. Recently, DHX15 was identified as a tumor-related factor. Although both autophagy and DHX15 are involved in cellul ...[more]