Ontology highlight
ABSTRACT:
SUBMITTER: Zaghlool SB
PROVIDER: S-EPMC7904950 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Zaghlool Shaza B SB Sharma Sapna S Molnar Megan M Matías-García Pamela R PR Elhadad Mohamed A MA Waldenberger Melanie M Peters Annette A Rathmann Wolfgang W Graumann Johannes J Gieger Christian C Grallert Harald H Suhre Karsten K
Nature communications 20210224 1
Blood circulating proteins are confounded readouts of the biological processes that occur in different tissues and organs. Many proteins have been linked to complex disorders and are also under substantial genetic control. Here, we investigate the associations between over 1000 blood circulating proteins and body mass index (BMI) in three studies including over 4600 participants. We show that BMI is associated with widespread changes in the plasma proteome. We observe 152 replicated protein asso ...[more]