Ontology highlight
ABSTRACT:
SUBMITTER: Shiha G
PROVIDER: S-EPMC7907074 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Shiha Gamal G Soliman Reham R Elbasiony Mohamed M Darwish Noureldien H E NHE Mousa Shaker A SA
Scientific reports 20210225 1
The new anti-hepatitis C virus (HCV) molecules improve treatment regimens and outcomes, but there are drawbacks. New combinations should target the HCV infectious cycle and be effective against all HCV genotypes. We developed the novel formulation Catvira, composed of epigallocatechingallate (EGCG) + sofosbuvir + ribavirin. Here, we compared Catvira to sofosbuvir + ribavirin tablets in patients with CHC genotype 4 in a randomized open-label efficacy and safety study. Treatment-naïve and treatmen ...[more]