Ontology highlight
ABSTRACT:
SUBMITTER: Nishida D
PROVIDER: S-EPMC7907144 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Nishida Daisuke D Arai Atsushi A Zhao Lijuan L Yang Mengyu M Nakamichi Yuko Y Horibe Kanji K Hosoya Akihiro A Kobayashi Yasuhiro Y Udagawa Nobuyuki N Mizoguchi Toshihide T
Scientific reports 20210225 1
Bone-resorbing osteoclasts are regulated by the relative ratio of the differentiation factor, receptor activator NF-kappa B ligand (RANKL) and its decoy receptor, osteoprotegerin (OPG). Dental tissue-localized-resorbing cells called odontoclasts have regulatory factors considered as identical to those of osteoclasts; however, it is still unclear whether the RANKL/OPG ratio is a key factor for odontoclast regulation in dental pulp. Here, we showed that odontoclast regulators, macrophage colony-st ...[more]