Ontology highlight
ABSTRACT:
SUBMITTER: Maekura K
PROVIDER: S-EPMC7907349 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Maekura Koji K Tsukamoto Satoshi S Hamada-Kanazawa Michiko M Takano Masaoki M
Scientific reports 20210225 1
Rimklb is a mammalian homologue of the E. coli enzyme RimK, which catalyzes addition of glutamic acid to the ribosomal protein S6. To date, no previous studies have shown any physiological role for Rimklb in mammals. In this study, using Western blotting, we found that Rimklb is distributed and expressed in mouse testis and heart. Rimklb was subsequently localized to the testicular Leydig cells using immunohistochemistry with an anti-Rimklb antibody. We generated a Rimklb mutant mouse in which a ...[more]