An update on the role of long non-coding RNAs in psoriasis.
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ABSTRACT: Abstract
Increasing evidence suggests that long non-coding RNAs (lncRNAs) are of vital importance for various biological processes, and dysregulation of lncRNAs is frequently associated with various diseases such as psoriasis. LncRNAs modulate gene expression at the transcriptional, post-transcriptional, and translational levels; however, the specific regulatory mechanisms of lncRNAs in psoriasis remain largely unexplored. This review provides an overview of recent studies investigating mechanisms and functions of lncRNAs in psoriasis, especially focusing on the role of lncRNAs in keratinocytes, T cells, and dendritic cells.
SUBMITTER: Song JK
PROVIDER: S-EPMC7909295 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Publications
An update on the role of long non-coding RNAs in psoriasis.
Song Jian-Kun JK Yin Shuang-Yi SY Li Wei W Li Xiao-Dong XD Luo Yue Y Luo Ying Y Xing Meng M Li Bin B Kuai Le L
Chinese medical journal 20201211 4
<h4>Abstract</h4>Increasing evidence suggests that long non-coding RNAs (lncRNAs) are of vital importance for various biological processes, and dysregulation of lncRNAs is frequently associated with various diseases such as psoriasis. LncRNAs modulate gene expression at the transcriptional, post-transcriptional, and translational levels; however, the specific regulatory mechanisms of lncRNAs in psoriasis remain largely unexplored. This review provides an overview of recent studies investigating ...[more]
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