Ontology highlight
ABSTRACT:
SUBMITTER: Elmariah H
PROVIDER: S-EPMC7911120 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Elmariah Hany H Brunstein Claudio G CG Bejanyan Nelli N
Life (Basel, Switzerland) 20210129 2
Allogeneic hematopoietic cell transplantation (HCT) is the only potentially curative therapy for a variety of hematologic diseases. However, this therapeutic platform is limited by an initial period when patients are profoundly immunocompromised. There is gradual immune recovery over time, that varies by transplant platform. Here, we review immune reconstitution after allogeneic HCT with a specific focus on two alternative donor platforms that have dramatically improved access to allogeneic HCT ...[more]