Ontology highlight
ABSTRACT:
SUBMITTER: Turk M
PROVIDER: S-EPMC7914623 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Turk Miray M Tatli Ozge O Alkan Hamza Furkan HF Ozfiliz Kilbas Pelin P Alkurt Gizem G Dinler Doganay Gizem G
Molecules (Basel, Switzerland) 20210206 4
Expression levels of the major mammalian autophagy regulator Beclin 1 and its interaction with Bcl-2 regulate the switch between autophagic cell survival and apoptotic cell death pathways. However, some of the regulators and the precise mechanisms of these processes still remain elusive. Bag-1 (Bcl-2 associated athanogene-1), a member of BAG family proteins, is a multifunctional pro-survival molecule that possesses critical functions in vital cellular pathways. Herein, we report the role of Bag- ...[more]