Ontology highlight
ABSTRACT:
SUBMITTER: Ragab A
PROVIDER: S-EPMC7915026 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Ragab Ahmed A Fouad Sawsan A SA Ali Ola A Abu OAA Ahmed Entsar M EM Ali Abeer M AM Askar Ahmed A AA Ammar Yousry A YA
Antibiotics (Basel, Switzerland) 20210205 2
Herein, a series of novel hybrid sulfaguanidine moieties, bearing 2-cyanoacrylamide <b>2a</b>-<b>d</b>, pyridine-2-one <b>3</b>-<b>10</b>, and 2-imino-2<i>H</i>-chromene-3-carboxamide <b>11</b>, <b>12</b> derivatives, were synthesized, and their structure confirmed by spectral data and elemental analysis. All the synthesized compounds showed moderate to good antimicrobial activity against eight pathogens. The most promising six derivatives, <b>2a</b>, <b>2b</b>, <b>2d</b>, <b>3a</b>, <b>8</b>, a ...[more]