Clinicopathological Correlates of ?? T Cell Infiltration in Triple-Negative Breast Cancer.
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ABSTRACT:
SUBMITTER: Boissiere-Michot F
PROVIDER: S-EPMC7918092 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Publications
Clinicopathological Correlates of γδ T Cell Infiltration in Triple-Negative Breast Cancer.
Boissière-Michot Florence F Chabab Ghita G Mollevi Caroline C Guiu Séverine S Lopez-Crapez Evelyne E Ramos Jeanne J Bonnefoy Nathalie N Lafont Virginie V Jacot William W
Cancers 20210212 4
The prognostic impact of the different tumor-infiltrating lymphocyte (TIL) subpopulations in solid cancers is still debated. Here, we investigated the clinicopathological correlates and prognostic impact of TILs, particularly of γδ T cells, in 162 patients with triple-negative breast cancer (TNBC). A high γδ T cell density (>6.625 γδ T cells/mm<sup>2</sup>) was associated with younger age (<i>p</i> = 0.008), higher tumor histological grade (<i>p</i> = 0.002), adjuvant chemotherapy (<i>p</i> = 0. ...[more]
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