Ontology highlight
ABSTRACT:
SUBMITTER: Almeida F
PROVIDER: S-EPMC7918990 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Almeida Filipe F Gameiro Andreia A Correia Jorge J Ferreira Fernando F
Animals : an open access journal from MDPI 20210215 2
Feline mammary carcinoma (FMC) is the third most common type of neoplasia in cats, sharing similar epidemiological features with human breast cancer. In humans, histone deacetylases (HDACs) play an important role in the regulation of gene expression, with HDAC inhibitors (HDACis) disrupting gene expression and leading to cell death. In parallel, microtubules inhibitors (MTIs) interfere with the polymerization of microtubules, leading to cell cycle arrest and apoptosis. Although HDACis and MTIs a ...[more]