The effect of vitamin C supplementation on lipid profile of type 2 diabetic patients: a systematic review and meta-analysis of clinical trials.

ABSTRACT:

Background and aims

We conducted a systematic review and meta-analysis of clinical trials evaluating the role of vitamin C supplementation on lipid profiles among diabetic patients to summarize the available findings.

Methods

A comprehensive search of PubMed, ScienceDirect, Google Scholar, and Cochrane Library databases was performed. Clinical trials conducted on adult type 2 diabetic patients evaluating the effect of vitamin C supplementation and reported lipid profiles (cholesterol (TC), triglycerides (TG), low density lipoprotein (LDL), high density lipoprotein (HDL)) were included. Weighted mean difference (WMD) was calculated.

Results

Vitamin C supplementation had no significant effect on TC (WMD = - 4.36 mg/dl (95% CI - 10.24, 1.52) p-value = 0.146), LDL level (

SUBMITTER: Tareke AA 

PROVIDER: S-EPMC7923652 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature