Ontology highlight
ABSTRACT:
SUBMITTER: Coronel-Oliveros C
PROVIDER: S-EPMC7924765 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Coronel-Oliveros Carlos C Cofré Rodrigo R Orio Patricio P
PLoS computational biology 20210218 2
Segregation and integration are two fundamental principles of brain structural and functional organization. Neuroimaging studies have shown that the brain transits between different functionally segregated and integrated states, and neuromodulatory systems have been proposed as key to facilitate these transitions. Although whole-brain computational models have reproduced this neuromodulatory effect, the role of local inhibitory circuits and their cholinergic modulation has not been studied. In t ...[more]