Lipid droplet dynamics in alcoholic fatty liver disease.
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ABSTRACT:
SUBMITTER: Schulze RJ
PROVIDER: S-EPMC7928432 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Publications
Lipid droplet dynamics in alcoholic fatty liver disease.
Schulze Ryan J RJ Ding Wen-Xing WX
Liver research 20190906 3-4
The rising incidence of alcohol-related liver disease (ALD) demands making urgent progress in understanding the fundamental molecular basis of alcohol-related hepatocellular damage. One of the key early events accompanying chronic alcohol usage is the accumulation of lipid droplets (LDs) in the hepatocellular cytoplasm. LDs are far from inert sites of neutral lipid storage; rather, they represent key organelles that play vital roles in the metabolic state of the cell. In this review, we will exa ...[more]
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