Fever as a predictor of adverse outcomes in COVID-19.
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ABSTRACT: Introduction
There are little data on outcomes of COVID-19 patients with the presence of fever compared to the presence of symptoms. We examined the associations between symptomology, presence of fever, and outcomes of a COVID-19 cohort.Methods
Between 23rd January to 30th April 2020, 554 COVID-19 patients were admitted to a tertiary hospital in Singapore. They were allocated into 4 groups based on symptomology and fever - Group 1: asymptomatic and afebrile, Group 2: symptomatic but afebrile, Group 3: febrile but asymptomatic, Group 4: symptomatic and febrile. The primary outcomes were intensive care unit (ICU) admissions and mortality. The composite end-point included ICU admissions, mortality or any COVID-19 related end-organ involvement.Results
There were differences in ferritin (p?=?0.003), C-reactive protein (CRP) levels (p?ConclusionIn this COVID-19 cohort, presence of fever was a predictor of adverse outcomes. This has implications on the management of febrile but asymptomatic COVID-19 patients.
SUBMITTER: Ws Chew N
PROVIDER: S-EPMC7928573 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Publications
Fever as a predictor of adverse outcomes in COVID-19.
Chew N W NW Ngiam J N JN Tham S M SM Lim Z Y ZY Li T Y W TYW Cen S S Yap E S ES Tambyah P A PA Santosa A A Cross G B GB Sia C-H CH
QJM : monthly journal of the Association of Physicians 20211201 10
<h4>Background/introduction</h4>There are little data on outcomes of COVID-19 patients with the presence of fever compared to the presence of symptoms.<h4>Aim</h4>We examined the associations between symptomology, presence of fever and outcomes of a COVID-19 cohort.<h4>Design and methods</h4>Between 23 January and 30 April 2020, 554 COVID-19 patients were admitted to a tertiary hospital in Singapore. They were allocated into four groups based on symptomology and fever-Group 1: asymptomatic and a ...[more]
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