Unknown

Dataset Information

0

Comparative analysis of perinatal outcomes and birth defects amongst adolescent and older Ugandan mothers: evidence from a hospital-based surveillance database.


ABSTRACT:

Background

Uganda has one of the highest adolescent pregnancy rates in sub-Saharan Africa. We compared the risk of adverse birth outcomes between adolescents (age 12-19 years) and mothers (age 20-34 years) in four urban hospitals.

Methods

Maternal demographics, HIV status, and birth outcomes of all live births, stillbirths, and spontaneous abortions delivered from August 2015 to December 2018 were extracted from a hospital-based birth defects surveillance database. Differences in the distributions of maternal and infant characteristics by maternal age groups were tested with Pearson's chi-square. Adjusted odds ratios (aORs) and 95% confidence intervals (CI) were calculated using logistic regression to compare the prevalence of adverse birth outcomes among adolescents to mothers 20-34 years.

Results

A total of 100,189 births were analyzed, with 11.1% among adolescent mothers and 89.0% among older mothers. Adolescent mothers had an increased risk of preterm delivery (aOR: 1.14; CI 1.06-1.23), low birth weight (aOR: 1.46; CI 1.34-1.59), and early neonatal deaths (aOR: 1.58; CI 1.23-2.02). Newborns of adolescent mothers had an increased risk of major external birth defects (aOR: 1.33; CI 1.02-1.76), specifically, gastroschisis (aOR: 3.20; CI 1.12-9.13) compared to mothers 20-34 years. The difference between the prevalence of gastroschisis among adolescent mothers (7.3 per 10,000 births; 95% CI 3.7-14.3) was statistically significant when compared to mothers 20-34 years (1.6 per 10,000 births; 95% CI 0.9-2.6).

Conclusions

This study found that adolescent mothers had an increased risk for several adverse birth outcomes compared to mothers 20-34 years, similar to findings in the region and globally. Interventions are needed to improve birth outcomes in this vulnerable population.

SUBMITTER: Serunjogi R 

PROVIDER: S-EPMC7934544 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature

altmetric image

Publications

Comparative analysis of perinatal outcomes and birth defects amongst adolescent and older Ugandan mothers: evidence from a hospital-based surveillance database.

Serunjogi Robert R   Barlow-Mosha Linda L   Mumpe-Mwanja Daniel D   Williamson Dhelia D   Valencia Diana D   Tinker Sarah C SC   Adler Michelle R MR   Namale-Matovu Joyce J   Kalibbala Dennis D   Nankunda Jolly J   Nabunya Evelyn E   Birabwa-Male Doreen D   Byamugisha Josaphat J   Musoke Philippa P  

Reproductive health 20210304 1


<h4>Background</h4>Uganda has one of the highest adolescent pregnancy rates in sub-Saharan Africa. We compared the risk of adverse birth outcomes between adolescents (age 12-19 years) and mothers (age 20-34 years) in four urban hospitals.<h4>Methods</h4>Maternal demographics, HIV status, and birth outcomes of all live births, stillbirths, and spontaneous abortions delivered from August 2015 to December 2018 were extracted from a hospital-based birth defects surveillance database. Differences in  ...[more]

Similar Datasets

| S-EPMC4631395 | biostudies-literature
| S-EPMC10576368 | biostudies-literature
| S-EPMC10112798 | biostudies-literature
| S-EPMC3897950 | biostudies-literature
| S-EPMC3472023 | biostudies-literature
| S-EPMC10666300 | biostudies-literature
| S-EPMC8273078 | biostudies-literature
| S-EPMC6851529 | biostudies-literature
| S-EPMC7665744 | biostudies-literature