Ontology highlight
ABSTRACT:
SUBMITTER: Lu L
PROVIDER: S-EPMC7951502 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Lu Lingxiang L Siu Juno C JC Lai Yihuan Y Lin Song S
Journal of the American Chemical Society 20201208 51
The construction of C(sp<sup>3</sup>)-Si bonds is important in synthetic, medicinal, and materials chemistry. In this context, reactions mediated by silyl radicals have become increasingly attractive but methods for accessing these intermediates remain limited. We present a new strategy for silyl radical generation via electroreduction of readily available chlorosilanes. At highly biased potentials, electrochemistry grants access to silyl radicals through energetically uphill reductive cleavage ...[more]