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Silylation reactions on nanoporous gold via homolytic Si-H activation of silanes.

ABSTRACT: Si-H bond activation is an important process implicated in many useful synthetic applications including silylation and transfer hydrogenation reactions. Herein we discovered homolytic activation of Si-H bonds on the surface of nanoporous gold (NPG), forming hydrogen radicals and [Au]-[Si] intermediates. By virtue of this new reactivity, we achieved highly selective mono and sequential alcoholysis of dihydrosilane. In addition, the amphiphilic nature of the [Au]-[Si] intermediate allows for a new bis-silylation reaction of cyclic ethers. The present work showcased that the surface reactivity of nanocatalysts may provide exciting opportunity for new reaction discovery.

SUBMITTER: Li H

PROVIDER: S-EPMC5982200 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature

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Silylation reactions on nanoporous gold <i>via</i> homolytic Si-H activation of silanes.

Li Hongbo H Guo Huifang H Li Zhiwen Z Wu Cai C Li Jing J Zhao Chunliang C Guo Shuangxi S Ding Yi Y He Wei W Li Yadong Y

Chemical science 20180430 21

Si-H bond activation is an important process implicated in many useful synthetic applications including silylation and transfer hydrogenation reactions. Herein we discovered homolytic activation of Si-H bonds on the surface of nanoporous gold (NPG), forming hydrogen radicals and [Au]-[Si] intermediates. By virtue of this new reactivity, we achieved highly selective mono and sequential alcoholysis of dihydrosilane. In addition, the amphiphilic nature of the [Au]-[Si] intermediate allows for a new ...[more]

PMID: 29910932

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