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Clinical outcomes of early gastric cardiac cancer treated with endoscopic submucosal dissection in patients with different indications.


ABSTRACT:

Background

Endoscopic submucosal dissection (ESD) has been accepted as a standard treatment for early gastric cardiac cancer (EGCC). Here, we investigate the clinical outcomes of the EGCC patients who underwent ESD in different indications.

Methods

From January 2011 to October 2019, we enrolled 502 EGCC lesions from 495 patients which were resected by ESD at our center. We retrospectively analyzed the short-term and long-term clinical outcomes among different indication groups.

Results

The number of the patients in the absolute indication (AI), expanded indication (EI) and beyond the expanded indication (BEI) groups was 265, 137 and 93, respectively. The en bloc resection rate was 100%, 100% and 98.9% (P?=?0.185). The complete resection rate was 99.3%, 98.5% and 74.5%, respectively (P?ConclusionThe efficacy for ESD patients in EI group was almost equal to the AI group. Patients in the BEI group showed generally favorable clinical outcomes and needed to be carefully checked after ESD. ESD may be an optional treatment for patients unsuitable for gastrectomy.

SUBMITTER: Fan T 

PROVIDER: S-EPMC7953789 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature

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Publications

Clinical outcomes of early gastric cardiac cancer treated with endoscopic submucosal dissection in patients with different indications.

Fan Ting T   Sun Qi Q   Cao Shouli S   Fan Xiangshan X   Huang Qin Q   Zhang Shu S   Lv Ying Y   Zhang Xiaoqi X   Ling Tingsheng T   Wang Lei L   Zou Xiaoping X   Xu Guifang G  

BMC gastroenterology 20210312 1


<h4>Background</h4>Endoscopic submucosal dissection (ESD) has been accepted as a standard treatment for early gastric cardiac cancer (EGCC). Here, we investigate the clinical outcomes of the EGCC patients who underwent ESD in different indications.<h4>Methods</h4>From January 2011 to October 2019, we enrolled 502 EGCC lesions from 495 patients which were resected by ESD at our center. We retrospectively analyzed the short-term and long-term clinical outcomes among different indication groups.<h4  ...[more]

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