Dataset Information

Association between Homocysteine Levels and Psoriasis: A Meta-Analysis.

ABSTRACT:

Background

Psoriasis is a multifactorial disease associated with an increased risk for metabolic syndrome and cardiovascular diseases. Elevated levels of homocysteine (Hcy) are a marker of cardiovascular risk. Several studies have evaluated the associations between psoriasis and Hcy levels; however, the results remain inconclusive.

Objective

We performed a systematic review of the literature and a meta-analysis to better understand the relationship between psoriasis and Hcy.

Methods

Five scientific databases (MEDLINE, Embase, Cochrane Library, Scopus, and Web of Science) were searched to identify relevant studies. A review of 307 publications identified 16 studies that directly assessed plasma levels of Hcy in psoriasis patients.