Ontology highlight
ABSTRACT:
SUBMITTER: Paderina DZ
PROVIDER: S-EPMC7999828 | biostudies-literature | 2021 Mar
REPOSITORIES: biostudies-literature
Paderina Diana Z DZ Boiko Anastasiia S AS Pozhidaev Ivan V IV Bocharova Anna V AV Mednova Irina A IA Fedorenko Olga Yu OY Kornetova Elena G EG Loonen Anton J M AJM Semke Arkadiy V AV Bokhan Nikolay A NA Ivanova Svetlana A SA
Journal of personalized medicine 20210305 3
<h4>Background</h4>Antipsychotic-induced metabolic syndrome (MetS) is a multifactorial disease with a genetic predisposition. Serotonin and its receptors are involved in antipsychotic-drug-induced metabolic disorders. The present study investigated the association of nine polymorphisms in the four 5-hydroxytryptamine receptor (<i>HTR</i>) genes <i>HTR1A</i>, <i>HTR2A</i>, <i>HTR3A</i>, and <i>HTR2C</i> and the gene encoding for the serotonin transporter <i>SLC6A4</i> with MetS in patients with s ...[more]