Ontology highlight
ABSTRACT:
SUBMITTER: Trzcinski JW
PROVIDER: S-EPMC8016167 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Trzciński Jakub W JW Morillas-Becerril Lucía L Scarpa Sara S Tannorella Marco M Muraca Francesco F Rastrelli Federico F Castellani Chiara C Fedrigo Marny M Angelini Annalisa A Tavano Regina R Papini Emanuele E Mancin Fabrizio F
Biomacromolecules 20201221 2
Herein we present an innovative approach to produce biocompatible, degradable, and stealth polymeric nanoparticles based on poly(lipoic acid), stabilized by a PEG-ended surfactant. Taking advantage of the well-known thiol-induced polymerization of lipoic acid, a universal and nontoxic nanovector consisted of a solid cross-linked polymeric matrix of lipoic acid monomers was prepared and loaded with active species with a one-step protocol. The biological studies demonstrated a high stability in bi ...[more]