Sleep Architecture in Children With Down Syndrome With and Without Obstructive Sleep Apnea.

ABSTRACT:

Objective

To characterize polysomnographic sleep architecture in children with Down syndrome and compare findings in those with and without obstructive sleep apnea.

Study design

Case series with retrospective review.

Setting

Single tertiary pediatric hospital (2005-2018).

Methods

We reviewed the electronic health records of patients undergoing polysomnography who were referred from a specialized center for children with Down syndrome (age, ≥12 months). Continuous positive airway pressure titration, oxygen titration, and split-night studies were excluded.

Results

A total of 397 children were included (52.4% male, 81.6% Caucasian). Mean age at the time of polysomnography was 4.7 years (range, 1.4-14.7); 79.4% had obstructive sleep apnea. Sleep variables we

SUBMITTER: Heubi CH 

PROVIDER: S-EPMC8021597 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature