Ontology highlight
ABSTRACT:
SUBMITTER: Chaudhary S
PROVIDER: S-EPMC8032398 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Chaudhary Shivesh S Lee Sol Ah SA Li Yueyi Y Patel Dhaval S DS Lu Hang H
eLife 20210224
Although identifying cell names in dense image stacks is critical in analyzing functional whole-brain data enabling comparison across experiments, unbiased identification is very difficult, and relies heavily on researchers' experiences. Here, we present a probabilistic-graphical-model framework, CRF_ID, based on Conditional Random Fields, for unbiased and automated cell identification. CRF_ID focuses on maximizing intrinsic similarity between shapes. Compared to existing methods, CRF_ID achieve ...[more]