Ontology highlight
ABSTRACT:
SUBMITTER: Seo Y
PROVIDER: S-EPMC8037333 | biostudies-literature | 2021 Mar
REPOSITORIES: biostudies-literature
Seo Yoojin Y Kang Min-Jung MJ Kim Hyung-Sik HS
International journal of molecular sciences 20210325 7
Mesenchymal stem cells (MSCs) have been developed as cell therapeutics for various immune disorders using their immunoregulatory properties mainly exerted by their paracrine functions. However, variation among cells from different donors, as well as rapid clearance after transplantation have impaired the uniform efficacy of MSCs and limited their application. Recently, several strategies to overcome this limitation have been suggested and proven in pre-clinical settings. Therefore, in this revie ...[more]